MAP3K10 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human MAP3K10.
Immunogen
Recombinant protein corresponding to human MAP3K10.
Sequence
LPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with MAP3K10 polyclonal antibody (Cat # PAB30773) shows strong cytoplasmic positivity in myocytes.Immunofluorescence
Immunofluorescent staining of A-431 cells with MAP3K10 polyclonal antibody (Cat # PAB30773) (Green) shows positivity in actin filaments. -
Gene Info — MAP3K10
Entrez GeneID
4294Protein Accession#
Q02779Gene Name
MAP3K10
Gene Alias
MLK2, MST
Gene Description
mitogen-activated protein kinase kinase kinase 10
Omim ID
600137Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq
Other Designations
MKN28 derived nonreceptor_type serine/threonine kinase|MKN28 kinase|mixed lineage kinase 2
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Interactome
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Pathway
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