USP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human USP2.
Immunogen
Recombinant protein corresponding to human USP2.
Sequence
QGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with USP2 polyclonal antibody (Cat # PAB30766).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human duodenum with USP2 polyclonal antibody (Cat # PAB30766) shows strong luminal membranous and cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of A-431 cells with USP2 polyclonal antibody (Cat # PAB30766) (Green) shows positivity in plasma membrane and cytoplasm. -
Gene Info — USP2
Entrez GeneID
9099Protein Accession#
O75604Gene Name
USP2
Gene Alias
UBP41, USP9
Gene Description
ubiquitin specific peptidase 2
Omim ID
604725Gene Ontology
HyperlinkGene Summary
Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).[supplied by OMIM
Other Designations
ubiquitin carboxyl-terminal hydrolase 2 variant 1|ubiquitin carboxyl-terminal hydrolase 2 variant 2|ubiquitin specific protease 12|ubiquitin specific protease 2|ubiquitin specific protease 9
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Interactome
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Disease
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