BLM polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human BLM.
Immunogen
Recombinant protein corresponding to human BLM.
Sequence
STLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with BLM polyclonal antibody (Cat # PAB30745) shows strong nuclear positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of A-431 cells with BLM polyclonal antibody (Cat # PAB30745) (Green) shows positivity in nucleus and cytoplasm. -
Gene Info — BLM
Entrez GeneID
641Protein Accession#
P54132Gene Name
BLM
Gene Alias
BS, MGC126616, MGC131618, MGC131620, RECQ2, RECQL2, RECQL3
Gene Description
Bloom syndrome
Gene Ontology
HyperlinkGene Summary
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq
Other Designations
Bloom syndrome protein
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Interactome
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Pathway
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Disease
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