BRIP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251MG sp cell lysates with BRIP1 polyclonal antibody (Cat # PAB30735).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with BRIP1 polyclonal antibody (Cat # PAB30735) shows strong nuclear positivity in cells in seminiferous ducts.
Immunofluorescence
Immunofluorescent staining of A-431 cells with BRIP1 polyclonal antibody (Cat # PAB30735) (Green) shows positivity in nucleus and nuclear membrane.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human BRIP1.
Immunogen
Recombinant protein corresponding to human BRIP1.
Sequence
FNKQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPEL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251MG sp cell lysates with BRIP1 polyclonal antibody (Cat # PAB30735).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with BRIP1 polyclonal antibody (Cat # PAB30735) shows strong nuclear positivity in cells in seminiferous ducts.Immunofluorescence
Immunofluorescent staining of A-431 cells with BRIP1 polyclonal antibody (Cat # PAB30735) (Green) shows positivity in nucleus and nuclear membrane. -
Gene Info — BRIP1
Entrez GeneID
83990Protein Accession#
Q9BX63Gene Name
BRIP1
Gene Alias
BACH1, FANCJ, FLJ90232, MGC126521, MGC126523, OF
Gene Description
BRCA1 interacting protein C-terminal helicase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq
Other Designations
BRCA1-associated C-terminal helicase 1|BRCA1-binding helicase-like protein BACH1|BRCA1-interacting protein 1
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Interactome
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Disease
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