FOSL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human FOSL2.
Immunogen
Recombinant protein corresponding to human FOSL2.
Sequence
EKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: NIH-3T3 cell lysate (mouse embryonic fibroblast cells) and Lane 2: NBT-II cell lysate (Wistar rat bladder tumor cells) with FOSL2 polyclonal antibody (Cat # PAB30711).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with FOSL2 polyclonal antibody (Cat # PAB30711) shows strong nuclear positivity in epidermal cells.Immunofluorescence
Immunofluorescent staining of U-251 MG with FOSL2 polyclonal antibody (Cat # PAB30711) (Green) shows positivity in nucleus but excluded from the nucleoli. -
Gene Info — FOSL2
Entrez GeneID
2355Protein Accession#
P15408Gene Name
FOSL2
Gene Alias
FLJ23306, FRA2
Gene Description
FOS-like antigen 2
Omim ID
601575Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq
Other Designations
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Interactome
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Disease
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