GSTZ1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human GSTZ1.
Immunogen
Recombinant protein corresponding to human GSTZ1.
Sequence
NLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: RT-4, Lane 2: U-251MG sp, Lane 3: human plasma (IgG/HSA depleted), Lane 4: human liver and Lane 5: human tonsil lysates with GSTZ1 polyclonal antibody (Cat # PAB30698).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with GSTZ1 polyclonal antibody (Cat # PAB30698) shows strong cytoplasmic and nuclear positivity in hepatocytes.Immunofluorescence
Immunofluorescent staining of U-2 OS with GSTZ1 polyclonal antibody (Cat # PAB30698) (Green) shows positivity in cytoplasm. -
Gene Info — GSTZ1
Entrez GeneID
2954Protein Accession#
O43708Gene Name
GSTZ1
Gene Alias
GSTZ1-1, MAAI, MAI, MGC2029
Gene Description
glutathione transferase zeta 1
Omim ID
603758Gene Ontology
HyperlinkGene Summary
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq
Other Designations
S-(hydroxyalkyl)glutathione lyase|glutathione S-alkyltransferase|glutathione S-aralkyltransferase|glutathione S-aryltransferase|glutathione s-transferase Zeta 1|maleylacetoacetate isomerase|maleylacetone isomerase
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Interactome
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Pathway
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Disease
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