EPS8 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with EPS8 polyclonal antibody (Cat # PAB30649) shows cytoplasmic positivity in exocrine glandular cells and islet cells.
Immunofluorescence
Immunofluorescent staining of U-251 MG with EPS8 polyclonal antibody (Cat # PAB30649) (Green) shows positivity in the Golgi apparatus.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human EPS8.
Immunogen
Recombinant protein corresponding to human EPS8.
Sequence
PKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with EPS8 polyclonal antibody (Cat # PAB30649) shows cytoplasmic positivity in exocrine glandular cells and islet cells.Immunofluorescence
Immunofluorescent staining of U-251 MG with EPS8 polyclonal antibody (Cat # PAB30649) (Green) shows positivity in the Golgi apparatus. -
Gene Info — EPS8
Entrez GeneID
2059Protein Accession#
Q12929Gene Name
EPS8
Gene Alias
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Gene Description
epidermal growth factor receptor pathway substrate 8
Omim ID
600206Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
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Interactome
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Disease
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