TRIM22 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with TRIM22 polyclonal antibody (Cat # PAB30631).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with TRIM22 polyclonal antibody (Cat # PAB30631) shows distinct nuclear and cytoplasmic positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of U-251 MG with TRIM22 polyclonal antibody (Cat # PAB30631) (Green) shows positivity in nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human TRIM22.
Immunogen
Recombinant protein corresponding to human TRIM22.
Sequence
NEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with TRIM22 polyclonal antibody (Cat # PAB30631).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with TRIM22 polyclonal antibody (Cat # PAB30631) shows distinct nuclear and cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of U-251 MG with TRIM22 polyclonal antibody (Cat # PAB30631) (Green) shows positivity in nucleus but excluded from the nucleoli. -
Gene Info — TRIM22
Entrez GeneID
10346Protein Accession#
Q8IYM9Gene Name
TRIM22
Gene Alias
GPSTAF50, RNF94, STAF50
Gene Description
tripartite motif-containing 22
Omim ID
606559Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. [provided by RefSeq
Other Designations
OTTHUMP00000069823|stimulated trans-acting factor (50 kDa)|tripartite binding motif 22|tripartite motif protein TRIM22
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Interactome
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