PKP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis with PKP2 polyclonal antibody (Cat # PAB30599).
Lane 1: Human cell line RT-4
Lane 2: Human cell line U-251MG sp
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with PKP2 polyclonal antibody (Cat # PAB30599) shows strong cytoplasmic positivity in myocytes.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PKP2 polyclonal antibody (Cat # PAB30599) shows positivity in cell junctions and nucleus but excluded from the nucleoli. Antibody staining is shown in green.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PKP2.
Immunogen
Recombinant protein corresponding to amino acids 72-194 of human PKP2.
Sequence
VGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRY
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1 - 4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
Western Blot (1:100 - 1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis with PKP2 polyclonal antibody (Cat # PAB30599).
Lane 1: Human cell line RT-4
Lane 2: Human cell line U-251MG spImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with PKP2 polyclonal antibody (Cat # PAB30599) shows strong cytoplasmic positivity in myocytes.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PKP2 polyclonal antibody (Cat # PAB30599) shows positivity in cell junctions and nucleus but excluded from the nucleoli. Antibody staining is shown in green. -
Gene Info — PKP2
Entrez GeneID
5318Protein Accession#
Q99959Gene Name
PKP2
Gene Alias
ARVD9, MGC177501
Gene Description
plakophilin 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq
Other Designations
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Interactome
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