IL16 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with IL16 polyclonal antibody (Cat # PAB30544) shows strong cytoplasmic positivity in cells of white pulp.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with IL16 polyclonal antibody (Cat # PAB30544) shows positivity in nucleus, plasma membrane and cytoplasm. Antibody staining is shown in green.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human IL16.
Immunogen
Recombinant protein corresponding to human IL16.
Sequence
QRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
The optimal working dilution should be determined by the end user. Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with IL16 polyclonal antibody (Cat # PAB30544) shows strong cytoplasmic positivity in cells of white pulp.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with IL16 polyclonal antibody (Cat # PAB30544) shows positivity in nucleus, plasma membrane and cytoplasm. Antibody staining is shown in green. -
Gene Info — IL16
Entrez GeneID
3603Protein Accession#
Q14005Gene Name
IL16
Gene Alias
FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16
Gene Description
interleukin 16 (lymphocyte chemoattractant factor)
Omim ID
603035Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000190849|OTTHUMP00000190850|interleukin 16|lymphocyte chemoattractant factor
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Interactome
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Disease
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