TANK polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of human cell line RT-4 with TANK polyclonal antibody (Cat # PAB30534).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bronchus with TANK polyclonal antibody (Cat # PAB30534) shows cytoplasmic and membranous positivity in respiratory epithelial cells.
Immunofluorescence
Immunofluorescent staining of human cell line Hep G2 with TANK polyclonal antibody (Cat # PAB30534) shows positivity in cytoplasm. Antibody staining is shown in green.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human TANK.
Immunogen
Recombinant protein corresponding to human TANK.
Sequence
EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of human cell line RT-4 with TANK polyclonal antibody (Cat # PAB30534).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bronchus with TANK polyclonal antibody (Cat # PAB30534) shows cytoplasmic and membranous positivity in respiratory epithelial cells.Immunofluorescence
Immunofluorescent staining of human cell line Hep G2 with TANK polyclonal antibody (Cat # PAB30534) shows positivity in cytoplasm. Antibody staining is shown in green. -
Gene Info — TANK
Entrez GeneID
10010Protein Accession#
Q92844Gene Name
TANK
Gene Alias
I-TRAF, TRAF2
Gene Description
TRAF family member-associated NFKB activator
Omim ID
603893Gene Ontology
HyperlinkGene Summary
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
TRAF family member-associated NF-KAPPA-B activator|TRAF interacting protein TANK
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Interactome
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Disease
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