KAT5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human KAT5.
Immunogen
Recombinant protein corresponding to amino acids 150 - 286 of human KAT5.
Sequence
KVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1 - 4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex using KAT5 polyclonal antibody (Cat # PAB30517) shows strong nuclear positivity in neurons.Immunofluorescence
Immunofluorescent staining of U-2 OS cells using KAT5 polyclonal antibody (Cat # PAB30517) shows positivity in nucleus (green) but excluded from the nucleoli. -
Gene Info — KAT5
Entrez GeneID
10524Protein Accession#
Q92993Gene Name
KAT5
Gene Alias
ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, cPLA2
Gene Description
K(lysine) acetyltransferase 5
Omim ID
601409Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Other Designations
HIV-1 Tat interactive protein, 60kDa|K-acetyltransferase 5|Tat interacting protein, 60kDa|cPLA2 interacting protein
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Interactome
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