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Last updated: 2017/3/19

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CCR6 polyclonal antibody

  • Catalog # : PAB30484
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant human CCR6.
  • Immunogen:
  • Recombinant protein corresponding to human CCR6.
  • Sequence:
  • KYNTQGSDVCEPKYQTVSEPIRWKLLML
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with CCR6 polyclonal antibody (Cat # PAB30484) shows strong cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction center at 1:50-1:200 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1235
  • Gene Name:
  • CCR6
  • Gene Alias:
  • BN-1,CD196,CKR-L3,CKR6,CKRL3,CMKBR6,DCR2,DRY-6,GPR-CY4,GPR29,GPRCY4,STRL22
  • Gene Description:
  • chemokine (C-C motif) receptor 6
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq
  • Other Designations:
  • G protein-coupled receptor 29,OTTHUMP00000017618,OTTHUMP00000017619,chemokine (C-C) receptor 6,chemokine receptor-like 3,seven-transmembrane receptor, lymphocyte, 22
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