SLC31A1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small intestine with SLC31A1 polyclonal antibody (Cat # PAB30474) shows moderate cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SLC31A1.
Immunogen
Recombinant protein corresponding to human SLC31A1.
Sequence
IARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small intestine with SLC31A1 polyclonal antibody (Cat # PAB30474) shows moderate cytoplasmic positivity in glandular cells at 1:200-1:500 dilution. -
Gene Info — SLC31A1
Entrez GeneID
1317Protein Accession#
O15431Gene Name
SLC31A1
Gene Alias
COPT1, CTR1, MGC75487, hCTR1
Gene Description
solute carrier family 31 (copper transporters), member 1
Omim ID
603085Gene Ontology
HyperlinkGene Summary
Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM
Other Designations
OTTHUMP00000021950|copper transport 1 homolog|copper transporter 1
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