CDH15 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CDH15.
Immunogen
Recombinant protein corresponding to human CDH15.
Sequence
TFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSH
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human smooth muscle with CDH15 polyclonal antibody (Cat # PAB30427) shows strong cytoplasmic positivity in smooth muscle cells at 1:50-1:200 dilution. -
Gene Info — CDH15
Entrez GeneID
1013Protein Accession#
P55291Gene Name
CDH15
Gene Alias
CDH14, CDH3, CDHM, MCAD
Gene Description
cadherin 15, type 1, M-cadherin (myotubule)
Omim ID
114019Gene Ontology
HyperlinkGene Summary
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq
Other Designations
M-cadherin|cadherin 15|cadherin 15, M-cadherin (myotubule)|cadherin-14|cadherin-3|muscle-cadherin|myotubule-cadherin
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Interactome
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Disease
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