DIAPH1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with DIAPH1 polyclonal antibody (Cat # PAB30386) shows strong cytoplasmic positivity in neuronal cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human DIAPH1.
Immunogen
Recombinant protein corresponding to human DIAPH1.
Sequence
SLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with DIAPH1 polyclonal antibody (Cat # PAB30386) shows strong cytoplasmic positivity in neuronal cells at 1:50-1:200 dilution. -
Gene Info — DIAPH1
Entrez GeneID
1729Protein Accession#
O60610Gene Name
DIAPH1
Gene Alias
DFNA1, DIA1, DRF1, FLJ25265, LFHL1, hDIA1
Gene Description
diaphanous homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000195047|OTTHUMP00000195048|diaphanous 1|diaphanous-1|diaphanous-related formin 1
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Interactome
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Pathway
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Disease
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