Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human ovary with TGM3 polyclonal antibody (Cat # PAB30377) shows strong cytoplasmic positivity in follicle cells at 1:200-1:500 dilution.
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq
OTTHUMP00000030008,TGase E,transglutaminase 3,transglutaminase E