Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with MAGEC1 polyclonal antibody (Cat # PAB30374) shows strong cytoplasmic and nuclear positivity in cells in seminiferous ducts at 1:50-1:200 dilution.
This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins. [provided by RefSeq