Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with DYNC1H1 polyclonal antibody (Cat # PAB30356) shows strong cytoplasmic positivity in basal cells of the seminiferous ducts at 1:50-1:200 dilution.
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq
cytoplasmic dynein 1 heavy chain 1,dynein heavy chain, cytosolic,dynein, cytoplasmic, heavy polypeptide 1,dynein, cytoplasmic-like