CD180 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with CD180 polyclonal antibody (Cat # PAB30355) shows strong cytoplasmic positivity in cells in white pulp at 1:500-1:1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CD180.
Immunogen
Recombinant protein corresponding to human CD180.
Sequence
DFQNNAIHYISREDMRSLEQAINLSLNFNGNNVKGIELGAFDSTVFQSLNFGGTPNLSVIFNGLQNSTTQSLWLGTFEDIDDEDISSAMLKGLCEMSVESLNLQEHRFSDISSTTFQCFTQLQELDLTATHLKGLPSGMKGLNLLKKL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with CD180 polyclonal antibody (Cat # PAB30355) shows strong cytoplasmic positivity in cells in white pulp at 1:500-1:1000 dilution. -
Gene Info — CD180
Entrez GeneID
4064Protein Accession#
Q99467Gene Name
CD180
Gene Alias
LY64, Ly78, MGC126233, MGC126234, RP105
Gene Description
CD180 molecule
Omim ID
602226Gene Ontology
HyperlinkGene Summary
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq
Other Designations
CD180 antigen|lymphocyte antigen-64, radioprotective, 105kDa
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Interactome
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Disease
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