USP11 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human USP11.
Immunogen
Recombinant protein corresponding to human USP11.
Sequence
ESGRERPLRAGESWFLVEKHWYKQWEAYVQGGDQDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLLPAAAWHYLVSWYGLEHGQPPIERKVIELPNIQKVEVYPVELLLVRHNDLGKSHTVQFS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with USP11 polyclonal antibody (Cat # PAB30334) shows distinct nuclear and cytoplasmic positivity of basal cells in seminiferous ducts at 1:50-1:200 dilution. -
Gene Info — USP11
Entrez GeneID
8237Protein Accession#
P51784Gene Name
USP11
Gene Alias
UHX1
Gene Description
ubiquitin specific peptidase 11
Omim ID
300050Gene Ontology
HyperlinkGene Summary
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq
Other Designations
deubiquitinating enzyme 11|ubiquitin carboxyl-terminal hydrolase, X-linked|ubiquitin specific protease 11|ubiquitin thiolesterase 11|ubiquitin-specific processing protease 11
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