F5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human F5.
Immunogen
Recombinant protein corresponding to human F5.
Sequence
MPSPSSPTLNDTFLSKEFNPLVIVGLSKDGTDYIEIIPKEEVQSSEDDYAEIDYVPYDDPYKTDVRTNINSSRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSEFVQRETDIEDSDDIPEDTT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with F5 polyclonal antibody (Cat # PAB30324) shows strong cytoplasmic positivity in Purkinje cells at 1:50-1:200 dilution. -
Gene Info — F5
Entrez GeneID
2153Protein Accession#
P12259Gene Name
F5
Gene Alias
FVL, PCCF
Gene Description
coagulation factor V (proaccelerin, labile factor)
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq
Other Designations
OTTHUMP00000032547|activated protein c cofactor|coagulation factor V|coagulation factor V jinjiang A2 domain|factor V Leiden|labile factor
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Interactome
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Disease
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