Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human adrenal gland with PINK1 polyclonal antibody (Cat # PAB30322) shows strong granular positivity in the cytoplasm of cortical cells at 1:200-1:500 dilution.
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq