CDH3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human oral mucosa with CDH3 polyclonal antibody (Cat # PAB30316) shows strong cytoplasmic and membranous positivity in squamous epithelial cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CDH3.
Immunogen
Recombinant protein corresponding to human CDH3.
Sequence
YNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human oral mucosa with CDH3 polyclonal antibody (Cat # PAB30316) shows strong cytoplasmic and membranous positivity in squamous epithelial cells at 1:50-1:200 dilution. -
Gene Info — CDH3
Entrez GeneID
1001Protein Accession#
P22223Gene Name
CDH3
Gene Alias
CDHP, HJMD, PCAD
Gene Description
cadherin 3, type 1, P-cadherin (placental)
Gene Ontology
HyperlinkGene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq
Other Designations
cadherin 3, type 1|calcium-dependent adhesion protein, placental
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Interactome
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Pathway
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Disease
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