PIGA polyclonal antibody

Catalog # PAB30310

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with PIGA polyclonal antibody (Cat # PAB30310) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against partial recombinant human PIGA.

    Immunogen

    Recombinant protein corresponding to human PIGA.

    Sequence

    FADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRII

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with PIGA polyclonal antibody (Cat # PAB30310) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
  • Gene Info — PIGA

    Entrez GeneID

    5277

    Protein Accession#

    P37287

    Gene Name

    PIGA

    Gene Alias

    GPI3, PIG-A

    Gene Description

    phosphatidylinositol glycan anchor biosynthesis, class A

    Omim ID

    311770

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. [provided by RefSeq

    Other Designations

    GLCNAC-PI synthesis protein|GPI anchor biosynthesis|OTTHUMP00000022959|phosphatidylinositol N-acetylglucosaminyltransferase subunit A|phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria)|phosphatidylinositol-glycan biosynthesis, clas

  • Interactome
  • Pathway
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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