ADAM8 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with ADAM8 polyclonal antibody (Cat # PAB30305) shows moderate cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ADAM8.
Immunogen
Recombinant protein corresponding to amino acids 28-111 of human ADAM8.
Sequence
QYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000 - 1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with ADAM8 polyclonal antibody (Cat # PAB30305) shows moderate cytoplasmic positivity in glandular cells. -
Gene Info — ADAM8
Entrez GeneID
101Protein Accession#
P78325Gene Name
ADAM8
Gene Alias
CD156, MGC134985, MS2
Gene Description
ADAM metallopeptidase domain 8
Omim ID
602267Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
CD156a antigen|OTTHUMP00000020792|a disintegrin and metalloproteinase domain 8|cell surface antigen MS2
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Interactome
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Disease
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