GP9 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human GP9.
Immunogen
Recombinant protein corresponding to amino acids 41-91 of human GP9.
Sequence
HGLTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDC
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with GP9 polyclonal antibody (Cat # PAB30303) shows strong cytoplasmic positivity in megakaryocytes. -
Gene Info — GP9
Entrez GeneID
2815Protein Accession#
P14770Gene Name
GP9
Gene Alias
CD42a, GPIX
Gene Description
glycoprotein IX (platelet)
Gene Ontology
HyperlinkGene Summary
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq
Other Designations
platelet glycoprotein IX
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Interactome
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Pathway
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Disease
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