VPREB1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with VPREB1 polyclonal antibody (Cat # PAB30292) shows moderate nuclear membrane positivity in hematopoietic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human VPREB1.
Immunogen
Recombinant protein corresponding to amino acids 20-138 of human VPREB1.
Sequence
QPVLHQPPAMSSALGTTIRLTCTLRNDHDIGVYSVYWYQQRPGHPPRFLLRYFSQSDKSQGPQVPPRFSGSKDVARNRGYLSISELQPEDEAMYYCAMGARSSEKEEREREWEEEMEPT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500 - 1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with VPREB1 polyclonal antibody (Cat # PAB30292) shows moderate nuclear membrane positivity in hematopoietic cells. -
Gene Info — VPREB1
Entrez GeneID
7441Protein Accession#
P12018Gene Name
VPREB1
Gene Alias
IGI, IGVPB, VPREB
Gene Description
pre-B lymphocyte 1
Omim ID
605141Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. [provided by RefSeq
Other Designations
CD179a|immunoglobulin iota chain
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