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LILRB4 polyclonal antibody

  • Catalog # : PAB30282
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant human LILRB4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 213-237 of human LILRB4.
  • Sequence:
  • LELIVSGSLEGPRPSPTRSVSTAAG
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with LILRB4 polyclonal antibody (Cat # PAB30282) shows strong cytoplasmic positivity in subset of non-germinal center cells.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • LILRB4
  • Gene Alias:
  • CD85K,HM18,ILT3,LILRB5,LIR-5,LIR5
  • Gene Description:
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
  • Gene Summary:
  • This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000068605,OTTHUMP00000068606,immunoglobulin-like transcript 3,leukocyte immunoglobulin-like receptor 5,leukocyte immunoglobulin-like receptor subfamily B member 4 soluble isoform,leukocyte immunoglobulin-like receptor, subfamily B, member 4,monoc
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