SLAMF6 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with SLAMF6 polyclonal antibody (Cat # PAB30278) shows strong cytoplasmic positivity in islets of Langerhans.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SLAMF6.
Immunogen
Recombinant protein corresponding to amino acids 40-115 of human SLAMF6.
Sequence
LPLEFPAGEKVNFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with SLAMF6 polyclonal antibody (Cat # PAB30278) shows strong cytoplasmic positivity in islets of Langerhans. -
Gene Info — SLAMF6
Entrez GeneID
114836Protein Accession#
Q96DU3Gene Name
SLAMF6
Gene Alias
KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000
Gene Description
SLAM family member 6
Omim ID
606446Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. [provided by RefSeq
Other Designations
NTBA receptor|OTTHUMP00000024348|activating NK receptor|natural killer-, T- and B-cell antigen
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Interactome
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Disease
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