CSF3R polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with CSF3R polyclonal antibody (Cat # PAB30266) shows strong cytoplasmic positivity in a subset of leukocytes and weak cytoplasmic staining in non-germinal center cells.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with CSF3R polyclonal antibody (Cat # PAB30266) shows moderate cytoplasmic positivity in trophoblastic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CSF3R.
Immunogen
Recombinant protein corresponding to amino acids 420-543 of human CSF3R.
Sequence
TPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGKTWA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500 - 1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with CSF3R polyclonal antibody (Cat # PAB30266) shows strong cytoplasmic positivity in a subset of leukocytes and weak cytoplasmic staining in non-germinal center cells.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with CSF3R polyclonal antibody (Cat # PAB30266) shows moderate cytoplasmic positivity in trophoblastic cells. -
Gene Info — CSF3R
Entrez GeneID
1441Protein Accession#
Q99062Gene Name
CSF3R
Gene Alias
CD114, GCSFR
Gene Description
colony stimulating factor 3 receptor (granulocyte)
Omim ID
138971Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq
Other Designations
CD114 antigen|OTTHUMP00000009703|OTTHUMP00000009704|OTTHUMP00000009705|colony stimulating factor 3 receptor|granulocyte colony stimulating factor receptor
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Interactome
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Pathway
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Disease
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