SIRPB1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SIRPB1.
Immunogen
Recombinant protein corresponding to amino acids 340-371 of human SIRPB1.
Sequence
VSKSYALEISAHQKEHGSDITHEPALAPTAPL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with SIRPB1 polyclonal antibody (Cat # PAB30263) shows strong cytoplasmic positivity in myocytes. -
Gene Info — SIRPB1
Entrez GeneID
10326Protein Accession#
O00241Gene Name
SIRPB1
Gene Alias
CD172b, DKFZp686A05192, FLJ26614, SIRP-BETA-1
Gene Description
signal-regulatory protein beta 1
Omim ID
603889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029992|OTTHUMP00000029993
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