SIRPB1 polyclonal antibody

Catalog # PAB30263

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with SIRPB1 polyclonal antibody (Cat # PAB30263) shows strong cytoplasmic positivity in myocytes.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against partial recombinant human SIRPB1.

    Immunogen

    Recombinant protein corresponding to amino acids 340-371 of human SIRPB1.

    Sequence

    VSKSYALEISAHQKEHGSDITHEPALAPTAPL

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:500)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with SIRPB1 polyclonal antibody (Cat # PAB30263) shows strong cytoplasmic positivity in myocytes.
  • Gene Info — SIRPB1

    Entrez GeneID

    10326

    Protein Accession#

    O00241

    Gene Name

    SIRPB1

    Gene Alias

    CD172b, DKFZp686A05192, FLJ26614, SIRP-BETA-1

    Gene Description

    signal-regulatory protein beta 1

    Omim ID

    603889

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000029992|OTTHUMP00000029993

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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