Western Blot (Cell lysate) analysis with SERPINA1 polyclonal antibody (Cat # PAB30249) at 1:250 - 1:500 dilution Lane 1: Human cell line RT-4 Lane 2: Human cell line U-251MG sp Lane 3: Human cell line A-431 Lane 4: Human liver tissue Lane 5: Human tonsil tissue
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with SERPINA1 polyclonal antibody (Cat # PAB30249) shows moderate extra-cellular positivity in tubule cells and positivity of plasma in blood vesse at 1:200 - 1:500 dilution.
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin,serine (or cysteine) proteinase inhibitor, clade A, member 1,serine proteinase inhibitor, clade A, member 1