Rabbit polyclonal antibody raised against synthetic peptide of human HSP90B1.
A synthetic peptide (conjugated with KLH) corresponding to amino acids 380-430 of human HSP90B1.
Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS, pH 7.4 (0.02% sodium azide).
Store at -20°C on dry atmosphere, lyophilized antibodies are stable. After reconstitution with deionized water, store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM