Rabbit polyclonal antibody raised against synthetic peptide of human MAPRE1.
A synthetic peptide (conjugated with KLH) corresponding to amino acids 130-180 of human MAPRE1.
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS, pH 7.4 (0.02% sodium azide).
Store at -20°C on dry atmosphere, lyophilized antibodies are stable. After reconstitution with deionized water, store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq
OTTHUMP00000030608,adenomatous polyposis coli-binding protein EB1