Rabbit polyclonal antibody raised against synthetic peptide of human COX4I1.
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human COX4I1.
ELISA (0.05-0.2 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS, pH 7.4 (0.02% sodium azide).
Store at -20°C on dry atmosphere, lyophilized antibodies are stable. After reconstitution with deionized water, store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Western Blot analysis of Lane 1: HeLa, Lane 2: HEK293, Lane 3: NIH/3T3, Lane 4: A431, Lane 5: Ramos, Lane 6: K562, Lane 7: HepG2, Lane 8: Lovo and Lane 9: mouse brain lysates with COX4I1 polyclonal antibody (Cat # PAB30201) at 1 ug/mL working concentration.
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq