Rabbit polyclonal antibody raised against synthetic peptide of human CDX2.
A synthetic peptide (conjugated with KLH) corresponding to amino acids 150-200 of human CDX2.
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS, pH 7.4 (0.02% sodium azide).
Store at -20°C on dry atmosphere, lyophilized antibodies are stable. After reconstitution with deionized water, store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
OTTHUMP00000018176,caudal type homeo box transcription factor 2,caudal type homeobox transcription factor 2