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Last updated: 2017/6/25

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BCL2L11 (phospho S69) polyclonal antibody

  • Catalog # : PAB30167
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial synthetic phosphopeptide of human BCL2L11.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding S69 of human BCL2L11.
  • Sequence:
  • P-A-Sp-P-G
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:100-1:200)
    Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1.0 mg/mL PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term use. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast carcinoma tissue with BCL2L11 (phospho S69) polyclonal antibody (Cat # PAB30167) (left) or the same antibody pre-incubated with blocking peptide (right).
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of methanol-fixed HeLa cells with BCL2L11 (phospho S69) polyclonal antibody (Cat # PAB30167).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • BCL2L11
  • Gene Alias:
  • BAM,BIM,BIM-alpha6,BIM-beta6,BIM-beta7,BOD,BimEL,BimL
  • Gene Description:
  • BCL2-like 11 (apoptosis facilitator)
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq
  • Other Designations:
  • BCL2-like 11,bcl-2 interacting mediator of cell death,bcl-2 interacting protein Bim,bcl-2-related ovarian death agonist
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