HMGB3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human HMGB3.
Immunogen
A synthetic peptide corresponding to C-terminus of human HMGB3.
Sequence
NLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKVEE
Host
Rabbit
Theoretical MW (kDa)
23
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human placenta tissue lysate with HMGB3 polyclonal antibody (Cat # PAB30133) at 0.3 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human intestine with HMGB3 polyclonal antibody (Cat # PAB30133) at 4-8 ug/mL working concentration. -
Gene Info — HMGB3
Entrez GeneID
3149GeneBank Accession#
NM_005342Protein Accession#
NP_005333;O15347Gene Name
HMGB3
Gene Alias
HMG2A, HMG4, MGC90319
Gene Description
high-mobility group box 3
Omim ID
300193Gene Ontology
HyperlinkGene Summary
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM
Other Designations
OTTHUMP00000025865|high-mobility group (nonhistone chromosomal) protein 4|non-histone chromosomal protein
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