GUSB polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human GUSB.
Immunogen
A synthetic peptide corresponding to C-terminus of human GUSB.
Sequence
VLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSPF
Host
Rabbit
Theoretical MW (kDa)
72
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GUSB polyclonal antibody (Cat # PAB30125) at 2.5 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung (A, B) with GUSB polyclonal antibody (Cat # PAB30125) at 4-8 ug/mL working concentration. -
Gene Info — GUSB
Entrez GeneID
2990GeneBank Accession#
NM_000181Protein Accession#
NP_000172;P08236Gene Name
GUSB
Gene Alias
FLJ39445, MPS7
Gene Description
glucuronidase, beta
Gene Ontology
HyperlinkGene Summary
The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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