GTF2IRD1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human GTF2IRD1.
Immunogen
A synthetic peptide corresponding to C-terminus of human GTF2IRD1.
Sequence
VIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSS
Host
Rabbit
Theoretical MW (kDa)
106
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of transfected 293T cell lysate with GTF2IRD1 polyclonal antibody (Cat # PAB30122) at 2.5 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with GTF2IRD1 polyclonal antibody (Cat # PAB30122) at 4-8 ug/mL working concentration. -
Gene Info — GTF2IRD1
Entrez GeneID
9569GeneBank Accession#
NM_016328Protein Accession#
NP_057412;Q9UHL9Gene Name
GTF2IRD1
Gene Alias
BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1
Gene Description
GTF2I repeat domain containing 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants. [provided by RefSeq
Other Designations
GTF2I repeat domain-containing 1|Williams-Beuren syndrome chromosome region 11|binding factor for early enhancer|general transcription factor 3|muscle TFII-I repeat domain-containing protein 1 alpha 1
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Interactome
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Pathway
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Disease
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