GTF2I polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human GTF2I.
Immunogen
A synthetic peptide corresponding to N-terminus of human GTF2I.
Sequence
ILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSH
Host
Rabbit
Theoretical MW (kDa)
110
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (0.2-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GTF2I polyclonal antibody (Cat # PAB30119) at 0.2-1 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas (A) and human skin (B) with GTF2I polyclonal antibody (Cat # PAB30119) at 4-8 ug/mL working concentration. -
Gene Info — GTF2I
Entrez GeneID
2969GeneBank Accession#
NM_033000Protein Accession#
NP_127493;P78347Gene Name
GTF2I
Gene Alias
BAP-135, BAP135, BTKAP1, DIWS, FLJ38776, FLJ56355, IB291, SPIN, TFII-I, WBS, WBSCR6
Gene Description
general transcription factor II, i
Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21. [provided by RefSeq
Other Designations
BTK-associated protein, 135kD|Bruton tyrosine kinase-associated protein 135|Williams-Beuren syndrome chromosome region 6
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Interactome
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Pathway
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