GPNMB polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human fetal lung tissue lysate with GPNMB polyclonal antibody (Cat # PAB30109) at 1 ug/mL working concentration.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with GPNMB polyclonal antibody (Cat # PAB30109) at 4-8 ug/mL working concentration.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human GPNMB.
Immunogen
A synthetic peptide corresponding to N-terminus of human GPNMB.
Sequence
DENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVN
Host
Rabbit
Theoretical MW (kDa)
63
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human fetal lung tissue lysate with GPNMB polyclonal antibody (Cat # PAB30109) at 1 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with GPNMB polyclonal antibody (Cat # PAB30109) at 4-8 ug/mL working concentration. -
Gene Info — GPNMB
Entrez GeneID
10457GeneBank Accession#
NM_002510Protein Accession#
NP_002501;Q14956Gene Name
GPNMB
Gene Alias
HGFIN, NMB
Gene Description
glycoprotein (transmembrane) nmb
Omim ID
604368Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
glycoprotein NMB|glycoprotein nmb-like protein|osteoactivin|transmembrane glycoprotein
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Interactome
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Disease
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