ETV6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human ETV6.
Immunogen
A synthetic peptide corresponding to C-terminus of human ETV6.
Sequence
VSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFR
Host
Rabbit
Theoretical MW (kDa)
53
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (0.2-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Jurkat cell lysate with ETV6 polyclonal antibody (Cat # PAB30054) at 0.2-1 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with ETV6 polyclonal antibody (Cat # PAB30054) at 4-8 ug/mL working concentration. -
Gene Info — ETV6
Entrez GeneID
2120GeneBank Accession#
NM_001987Protein Accession#
NP_001978;P41212Gene Name
ETV6
Gene Alias
TEL, TEL/ABL
Gene Description
ets variant 6
Gene Ontology
HyperlinkGene Summary
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq
Other Designations
TEL oncogene|TEL1 oncogene|ets variant gene 6 (TEL oncogene)
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Interactome
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Pathway
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Disease
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