APTX polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of human NCI-H226 cell lysate with APTX polyclonal antibody (Cat # PAB29964) at 2.5 ug/mL working concentration.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with APTX polyclonal antibody (Cat # PAB29964) at 4-8 ug/mL working concentration.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human APTX.
Immunogen
A synthetic peptide corresponding to C-terminus of human APTX.
Sequence
VIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ
Host
Rabbit
Theoretical MW (kDa)
38
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of human NCI-H226 cell lysate with APTX polyclonal antibody (Cat # PAB29964) at 2.5 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with APTX polyclonal antibody (Cat # PAB29964) at 4-8 ug/mL working concentration. -
Gene Info — APTX
Entrez GeneID
54840GeneBank Accession#
NM_175073Protein Accession#
NP_778243;Q7Z2E3Gene Name
APTX
Gene Alias
AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, FLJ20157, MGC1072
Gene Description
aprataxin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000021188|ataxia 1, early onset with hypoalbuminemia
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Interactome
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Disease
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