CD151 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human CD151.
Immunogen
A synthetic peptide corresponding to C-terminus of human CD151.
Sequence
HCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYK
Host
Rabbit
Theoretical MW (kDa)
28
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunofluorescence (1:100)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of A549 cell lysate with CD151 polyclonal antibody (Cat # PAB29946) at 1 ug/mL working concentration.Immunofluorescence
Immunofluorescent staining of human nasal epithelial cells with CD151 polyclonal antibody (Cat # PAB29946) at 1:100 dilution. -
Gene Info — CD151
Entrez GeneID
977GeneBank Accession#
NM_139030Protein Accession#
NP_620599;P48509Gene Name
CD151
Gene Alias
GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
Gene Description
CD151 molecule (Raph blood group)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq
Other Designations
CD151 antigen|CD151 antigen (Raph blood group)|OTTHUMP00000164434|hemidesmosomal tetraspanin CD151|membrane glycoprotein SFA-1|platelet surface glycoprotein gp27|platelet-endothelial cell tetraspan antigen 3
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