TNFRSF18 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 0.2-1 ug/mL working concentration.
Western Blot (Cell lysate)
Western Blot analysis of HCT116 cell lysate with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 1 ug/mL working concentration.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 4-8 ug/mL working concentration.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human TNFRSF18.
Immunogen
A synthetic peptide corresponding to C-terminus of human TNFRSF18.
Sequence
LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Host
Rabbit
Theoretical MW (kDa)
26
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 0.2-1 ug/mL working concentration.Western Blot (Cell lysate)
Western Blot analysis of HCT116 cell lysate with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 1 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain with TNFRSF18 polyclonal antibody (Cat # PAB29936) at 4-8 ug/mL working concentration. -
Gene Info — TNFRSF18
Entrez GeneID
8784GeneBank Accession#
NM_004195Protein Accession#
NP_004186;Q9Y5U5Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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Pathway
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Disease
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