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Last updated: 2016/10/23

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MXI1 polyclonal antibody

  • Catalog # : PAB29927
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of human MXI1.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human MXI1.
  • Sequence:
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 26
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
    Western Blot (0.2-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (2% sucrose, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot analysis of human fetal brain tissue lysate with MXI1 polyclonal antibody (Cat # PAB29927) at 0.2-1 ug/mL working concentration.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with MXI1 polyclonal antibody (Cat # PAB29927) at 4-8 ug/mL working concentration.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4601
  • Protein Accession#:
  • NP_569157;P50539
  • Gene Name:
  • MXI1
  • Gene Alias:
  • MAD2,MGC43220,MXD2,MXI,bHLHc11
  • Gene Description:
  • MAX interactor 1
  • Gene Summary:
  • Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
  • Other Designations:
  • MAX dimerization protein 2,MAX interacting protein 1,MAX-interacting protein 1,Max-related transcription factor,OTTHUMP00000020467,OTTHUMP00000020468,OTTHUMP00000020469
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