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MCM6 polyclonal antibody

  • Catalog # : PAB29921
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial synthetic protein of human MCM6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 771-820 of human MCM6.
  • Sequence:
  • RIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLE
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 90
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:250)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C for up to one week. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HepG2 cell lysate with MCM6 polyclonal antibody (Cat # PAB29921).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human intestine with MCM6 polyclonal antibody (Cat # PAB29921).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4175
  • Gene Name:
  • MCM6
  • Gene Alias:
  • MCG40308,Mis5,P105MCM
  • Gene Description:
  • minichromosome maintenance complex component 6
  • Gene Summary:
  • The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor MCM6,MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe),MIS5 homolog,minichromosome maintenance deficient (mis5, S. pombe) 6,minichromosome maintenance deficient 6 homolog
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