MAT1A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial synthetic protein of human MAT1A.
Immunogen
A synthetic peptide corresponding to amino acids 21-70 of human MAT1A.
Sequence
TSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGE
Host
Rabbit
Theoretical MW (kDa)
43
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:250)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C for up to one week. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate with MARVELD3 polyclonal antibody MAT1A polyclonal antibody (Cat # PAB29918).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with MAT1A polyclonal antibody (Cat # PAB29918). -
Gene Info — MAT1A
Entrez GeneID
4143Protein Accession#
Q00266Gene Name
MAT1A
Gene Alias
MAT, MATA1, SAMS, SAMS1
Gene Description
methionine adenosyltransferase I, alpha
Gene Ontology
HyperlinkGene Summary
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000019971|S-adenosylmethionine synthetase
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Interactome
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Disease
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